Our Company

Humanity

We are a biotechnology company with one specific mission: Advance humanity by engineering cell therapies that are safer, more effective, and more broadly accessible.

Our Story

founder doctor david hilbert
2014
AUGUST 2014

Arcellx was founded with the goal of adding control and adaptability to the potential of cell therapy.

research and development droplet
2015
APRIL 2015

Received seed money to start the development of what would become the D-Domain binding scaffold in an 800 sq. ft. tech incubator space in Gaithersburg, MD.

d domain protein
2016
WINTER 2016/2017

The initial success of the fully synthetic D-Domain, along with the prototypes of the first ARC-SparX platform, helps secure Series A funding, enabling the team to expand operations.

female scientist in new lab
2018
SEPTEMBER 2018

Construction began on what is now the Gaithersburg facility.

arc sparx protein
2019
OCTOBER 2019

Arcellx receives IND approval from the FDA for CART-ddBCMA and closed Series B funding to kick-start clinical trials and advance pipeline of ARC-SparX therapies.

ddbcma protein
2020
FEBRUARY 2020

The first patient is dosed with CART-ddBCMA for the treatment of relapsed or refractory multiple myeloma.

arcellx patient one
2020
DECEMBER 2020

The data from the company’s ongoing Phase 1 Study of CART-ddBCMA presented at ASH.

ddbcma and aclx-001 protein
2021
APRIL 2021

Arcellx received IND approval from the FDA for ACLX-001, a controllable cell therapy that uses the ARC-SparX platform for the treatment of multiple myeloma.

CEO rami elghandour
2021
JUNE 2021

Arcellx secures Series C funding to continue advancing CART-ddBCMA and ACLX-001.

Leadership

Rami Elghandour
Rami Elghandour
Rami Elghandour
Chairman and
Chief Executive Officer
Christopher Heery
Christopher Heery
Christopher Heery, MD
Chief Medical Officer
Kate Aiken
Kate Aiken
Kate Aiken
Chief People Officer
Michael Dombeck
Michael Dombeck
Michael Dombeck, MBA, MPP
Chief Operating Officer
Narinder Singh
Narinder Singh
Narinder Singh
Chief Technical Officer
Neeraj Teotia
Neeraj Teotia
Neeraj Teotia
Chief Commercial Officer
David Tice
David Tice
David Tice, PhD
Chief Scientific Officer
Aileen Fernandes
Aileen Fernandes
Aileen Fernandes
Vice President, Strategy
Brad Gliner
Brad Gliner
Brad Gliner
Vice President, Clinical Research and Regulatory Affairs
Grace Halteh
Grace Halteh
Grace Halteh, MS, PMP
Vice President, Quality
Shashi Kaithamana
Shashi Kaithamana
Shashi Kaithamana, PhD
Vice President, Protein Sciences
Myesha Lacy
Myesha Lacy
Myesha Lacy
Vice President, Investor Relations
Brian Murphy
Brian Murphy
Brian Murphy, PhD
Vice President, Cell Process Sciences
rami elghandour at waterfall
Rami Elghandour
Chairman and
Chief Executive Officer

Rami joined Arcellx in 2021 and serves as our Chairman and Chief Executive Officer. Most recently, Rami served as President and CEO of Nevro, beginning in 2012. Under his leadership, Nevro grew from a small private company to a public company approaching $400m in revenue and a leader in neuromodulation. Prior to Nevro, Rami was an investor with Johnson & Johnson Development Corporation (JJDC), where he led several investments including Nevro’s Series B Financing and served on the Board of Directors of several private companies including Nevro’s. Prior to joining JJDC, Rami was a Design Engineer for Advanced Neuromodulation Systems, Inc. where he led firmware design and development on several implantable spinal cord stimulators. Rami earned recognition as an EY Entrepreneur of the Year, as one of the top CEOs in the US and as one of the top CEOs for women and diversity. He is a recipient of the Bill Campbell award by Watermark for his influence, impact, and advocacy in promoting women and women’s issues. Rami received an MBA from the Wharton School of Business at the University of Pennsylvania and holds a BS in Electrical and Computer Engineering from Rutgers University School of Engineering.

Chris Heery
Christopher Heery, MD
Chief Medical Officer

Chief Medical Officer at Arcellx since April 2021. Prior to that, he served as Chief Medical Officer of Precision BioSciences and Bavarian Nordic. At Precision, he oversaw the clinical development of one of the first allogeneic CAR-T cell platforms and provided clinical insight into clinical efforts for gene editing therapeutics. While at Bavarian Nordic, he oversaw clinical development programs for its immune-oncology and infectious disease vaccine portfolio. Prior to his roles in biotech, he was head of the Clinical Trials Group of the Laboratory of Tumor Immunology and Biology at the National Cancer Institute (NCI). He joined the NCI Medical Oncology Branch as a Medical Oncology Fellow in 2009 and also held an Adjunct Appointment in the Genitourinary Malignancies Branch. At NCI, Dr. Heery was part of the larger effort of the Laboratory of Tumor Immunology and Biology to create new immunotherapies for the treatment of cancer. Dr. Heery is board-certified in Medical Oncology and Internal Medicine and completed his internal medicine residency at the University of Illinois at Chicago after receiving his MD from East Carolina University Brody School of Medicine. Dr. Heery also holds a BA in English Literature from Duke University.

Kate Aiken
Kate Aiken
Chief People Officer

Kate, an accomplished human resources business leader, brings more than 20 years of cross-industry experience, building and managing high-caliber HR organizations and partnering with business leaders to support the growth of industry-leading companies. Kate joins Arcellx from McKesson Corporation where she held roles with increasing responsibility since 2013, most recently serving as Senior Vice President, Human Resources, as part of the company’s Prescription Technology Solutions business unit. In this role Kate was part of an HR transformation that integrated a disruptive start-up into McKesson, which served as a springboard for her interest in rejoining a smaller, entrepreneurial company. Prior to McKesson, Kate spent 10 years at Gap, Inc. in several leading roles, most recently as Vice President, Human Resources. From 1999-2003, Kate was Vice President and Head of Human Resources at Oxygen Media, a start-up in the media and entertainment space. Kate holds an MBA in Business Strategy from New York University and a BA in Government from Dartmouth College.

Michael Dombeck
Michael Dombeck, MBA, MPP
Chief Operating Officer

Mike brings nearly 25 years of experience in pharma and biotech strategy and licensing. Most recently, Mike served as SVP of Corporate Development for Precision BioSciences, where he led transactions worth more than $2 billion, including a CAR-T co-development and co-promotion partnership with Baxalta that won the 2016 LES Deal of Distinction award, and in vivo gene editing collaborations with Gilead and The University of Pennsylvania’s Gene Therapy Program. Previously, Mike worked at GlaxoSmithKline in R&D Strategy and Portfolio Management, supporting portfolio analysis, business development, innovations in clinical trial design, evaluation and adoption of digital transformation initiatives, and optimization of global IP filings. Mike has worked with a wide range of start-up, small, medium, and large therapeutics companies, both private and public, and was a co-founder of Cempra Pharmaceuticals. Mike holds an MBA from Duke University’s Fuqua School of Business, an MPP. from Duke University’s Sanford School of Public Policy, and a BS in Biology from the Duke University Trinity College of Arts and Science.

Narinder Singh
Narinder Singh
Chief Technical Officer

Narinder joined Arcellx in Oct 2021 and serves as our Chief Technical Officer. Narinder has over two decades of technical and operational leadership experience in end-to-end biopharmaceutical clinical development, commercialization, and life cycle management. Previously, Narinder was CTO for Forte Biosciences, and prior to Forte, he served as EVP Technical Operations at Aimmune Inc. Prior to Aimmune, Narinder led neoantigen-based personalized cancer vaccine and T cell therapy development as SVP, Pharmaceutical Sciences and Manufacturing at Genocea. Prior to Genocea, Narinder served in a variety of technical leadership roles in drug product and combination device development, commercialization, and manufacturing operations at Momenta Pharmaceuticals and at Amgen. Narinder holds a B.Tech/M.Tech in Biochemical Engineering and Biotechnology from the Indian Institute of Technology, Delhi, an MS in Chemical Engineering from the University of Houston, and an MBA from the UCLA Anderson School of Management.

Neeraj Teotia
Neeraj Teotia
Chief Commercial Officer

Neeraj joined Arcellx in April 2021 and serves as our Chief Commercial Officer. Prior to joining Arcellx, Neeraj served as the Vice President of Marketing at Nevro. Over his 7 years at Nevro, he and his team set and executed commercial plans for a business that grew to ~$400 MM. His responsibilities included product and clinical portfolio strategy, branding, demand generation, key thought leader engagement, professional education, sales analytics and sales training. Prior to Nevro, Neeraj worked in the medical device sector at Johnson & Johnson for 17 years where he had various roles within Marketing, Licensing & Acquisitions and Research & Development. Neeraj received an MBA from the Kellogg School of Management at Northwestern University and has a BS in Electrical Engineering from the University of Illinois at Urbana-Champaign.

David Tice
David Tice, PhD
Chief Scientific Officer

David has served as Chief Scientific Officer since July 2021 and has over 20 years of biopharmaceutical research and drug development experience in oncology. Prior to joining Arcellx in 2020 as Vice President, Research and Translational Sciences, David spent 18 years at MedImmune, the global biologics research and development unit of AstraZeneca, where he held roles of increasing responsibility. While serving as the head of the antibody drug conjugate strategic area at AstraZeneca, David managed a portfolio of over 20 pipeline projects spanning discovery to Phase I. Prior to this experience, David worked at Genentech where he focused on genomics-based target discovery and monoclonal antibody targeting in cancer. David received his BS in Biology from Virginia Tech before receiving his PhD from the University of Virginia.

Aileen Fernandes
Aileen Fernandes
Vice President, Strategy

Aileen joined Arcellx in 2021 and currently serves as our Vice President of Strategy. Prior to joining Arcellx, Aileen held many roles with increasing responsibility at Nevro Corporation including Chief of Staff to the Chief Executive Officer, Associate Director, Business Development and Strategy, and as a Director of Marketing where she was instrumental in leading the go-to-market commercial strategy for a new clinical indication. Prior to Nevro, Aileen was a management consultant at Deloitte Consulting, partnering with a wide range of companies across the healthcare sector, and held business development and marketing roles at multiple digital health startups. Aileen started her career at Morgan Stanley where she was a Finance Analyst. Aileen received an MBA from the Wharton School of the University of Pennsylvania and holds a BA in Economics from the Wharton School of the University of Pennsylvania.

Brad Gliner
Brad Gliner
Vice President, Clinical Research and Regulatory Affairs

Brad joined Arcellx in March 2021, bringing over 30 years of experience in developing, testing, and commercializing medical technologies. Most recently, Brad served as VP of Clinical and Regulatory for Nevro, leading the clinical trials and regulatory approvals to bring a more effective spinal cord stimulation system to patients with chronic pain. Prior to this, Brad was VP of Research at Northstar Neuroscience, investigating numerous neuromodulation applications such as hemiparesis following stroke, major depressive disorder, movement disorders, and tinnitus. He was co-founder and Director of Research at Heartstream, which revolutionized automatic external defibrillators (AEDs), expanding their use from professional medical providers to ubiquitous availability. Brad received an MS degree in Biomedical Engineering from Johns Hopkins University and a BS in Electrical Engineering from the University of Illinois, Urbana-Champaign, IL.

Grace Halteh
Grace Halteh, MS, PMP
Vice President, Quality

Grace joined Arcellx in August 2021, bringing over 25 years of experience in life sciences Quality & Compliance, Operations Excellence, and Project Management. As a Quality professional, Grace has recognized expertise in Quality Management & Compliance, inspection readiness, vendor oversight programs, clinical study execution, and due diligence initiatives. She helped lead Global Health Authorities inspections, resulting in the successful registration of multiple biologics and small molecule products. Prior to joining Arcellx, Grace was the Executive Director of Quality Management and a member of the Operations Executive Leadership team at Exelixis. Earlier in her career, Grace held various Quality and Operations leadership roles at Nektar Therapeutics, Jazz Pharmaceuticals, Genentech, Janssen AI—a Johnson & Johnson company—and Elan Pharmaceuticals. Grace holds an MS in Systems Management and a BS in Cell and Molecular Biology.

Shashi Kaithamana
Shashi Kaithamana, PhD
Vice President, Protein Sciences

Shashi has over 25 years of experience in biological CMC development and manufacturing from preclinical development through commercialization. Prior to joining Arcellx, Shashi was head of Process Development at Jazz. Previously, Shashi held various CMC leadership positions at Alexion, Synageva, Zyngenia, Teva, Cogenesys, and Human Genome Sciences. Shashi holds a PhD in Biochemistry.

Myesha Lacy
Myesha Lacy
Vice President, Investor Relations

Myesha joined Arcellx in June 2021, bringing over 25 years of experience as a communications professional providing strategy, development, and execution of internal and external communications programs for publicly traded pharmaceutical and biotechnology companies. Most recently, Myesha was Vice President, Investor Relations and Corporate Communications at Adverum Biotechnologies. Prior to this Myesha held the same role at Global Blood Therapeutics, Inc., a $3 billion market capitalization company. Previously, Myesha led the integrated communications function at ZS Pharma, Inc. (acquired by AstraZeneca PLC), Hyperion Therapeutics, Inc. (acquired by Horizon Pharma), and served in various communications roles with increasing responsibility at other publicly traded biotechnology companies. Myesha earned a BA in Business from Holy Names University.

Brian Murphy
Brian Murphy, PhD
Vice President, Cell Process Sciences

Prior to Arcellx, Brian held multiple roles within Bristol Myers Squibb (formerly Celgene) where he worked over a decade on the development and commercialization of cellular therapies. Most recently, he was Senior Director of Process Engineering in Global Manufacturing Science and Technology, where he was responsible for late-stage lifecycle management, facility design, and technical transfer for multiple CAR-T assets. Brian has led technical transfers to internal sites and CMOs, oversaw the PPQ program for a CAR-T product, and contributed to BLA/MAA submissions. Brian previously led the Process Development department in the development of allogeneic cell therapies, represented Technical Operations on global project teams, and led teams in Analytical Development. Brian oversaw the CMC sections for multiple IND submissions for new therapeutic candidates, and he has a history of working with health authorities on novel products from pre-IND through pre-BLA meetings. Prior to working in cell and gene therapies, Brian worked in vaccine manufacturing at Merck. Brian has a PhD in Chemical and Biomolecular Engineering from the University of Pennsylvania.

Board of Directors

Rami joined Arcellx in 2021 and serves as our Chairman and Chief Executive Officer. Most recently, Rami served as President and CEO of Nevro, beginning in 2012. Under his leadership, Nevro grew from a small private company to a public company approaching $400m in revenue and a leader in neuromodulation. Prior to Nevro, Rami was an investor with Johnson & Johnson Development Corporation (JJDC), where he led several investments including Nevro’s Series B Financing and served on the Board of Directors of several private companies including Nevro’s. Prior to joining JJDC, Rami was a Design Engineer for Advanced Neuromodulation Systems, Inc. where he led firmware design and development on several implantable spinal cord stimulators. Rami earned recognition as an EY Entrepreneur of the Year, as one of the top CEOs in the US and as one of the top CEOs for women and diversity. He is a recipient of the Bill Campbell award by Watermark for his influence, impact, and advocacy in promoting women and women’s issues. Rami received an MBA from the Wharton School of Business at the University of Pennsylvania and holds a BS in Electrical and Computer Engineering from Rutgers University School of Engineering.

Ali is a general partner at New Enterprise Associates (NEA). Prior to NEA, he held positions at The Medicines Company, Morgan Stanley Venture Partners, and Lehman Brothers. He has been a member of the Board of Directors of Genocea Biosciences, Oyster Point Pharma, Monte Rosa Therapeutics, Nkarta, Inc., CRISPR Therapeutics, Adaptimmune Therapeutics, Black Diamond Therapeutics, CVRx, Minerva Surgical, and was on the board of Nevro Corp. Ali received a BS from Duke University, an MBA from the Wharton School of Business at the University of Pennsylvania, and an MD from the University of Pennsylvania School of Medicine.

Raymond has served as a member of our board of directors since November 2021. Dr. Camahort has been employed at Novo Ventures (US) Inc. in Boston, Massachusetts since 2015, where he served as an associate from 2015 to 2019 and a principal from January 2020 to present. Dr. Camahort has also served on the board of directors of Inspirna, Inc. since October 2021. He has over 15 years of combined research, business development, and venture capital experience, with expertise in biochemistry, molecular biology, and genetics. Dr. Camahort was an associate at the Harvard University Office of Technology Development from September 2013 to October 2015 where he worked to commercialize technologies developed in both chemistry and stem cell/regenerative biology. Dr. Camahort completed a National Institute of Health (NIH) post-doctoral training fellowship at Harvard University from July 2009 to September 2013 while concurrently holding a business development position at Partners Healthcare Research Ventures and Licensing from February 2013 to August 2013. Dr. Camahort holds a PhD from the University of Kansas in biochemistry and molecular biology, and a BS in biological sciences from the University of California Santa Barbara.

Jill is a Partner at SR One. Previously, Jill’s background is in corporate development and partnering in biotech companies, including Dynavax Technologies (NASDAQ: DVAX). Jill also worked as a consultant, specializing in health care. Jill is a member of the Board of Directors of HotSpot Therapeutics and Odyssey Therapeutics. Jill received her BS from Duke University and her MS in Biochemistry, Cellular and Molecular Biology from Johns Hopkins University.

Dr. Kavita Patel is currently a primary care physician in Washington DC. She is also a nonresident Fellow at the Brookings Institution where she concentrates on a number of efforts including delivery system reforms and cost containment. Recently, she was a system level executive at Johns Hopkins Health System with oversight of clinical integration and network contracting . Dr. Patel was previously a Director of Policy for The White House under President Obama and a Deputy Staff Director to the late Senator Edward Kennedy, where she focused on pandemic preparedness and health care reform. Her prior research in healthcare quality and community approaches to mental illness have earned national recognition and she has published numerous papers and book chapters on healthcare reform and health policy.

David is a senior finance executive with more than 25 years of experience in the life sciences industry. David served as Executive Vice President and Chief Financial Officer of Ra Pharma until May 2020, following its acquisition by UCB. Prior to Ra Pharma, David was Senior Vice President and Chief Financial Officer of Tetraphase Pharmaceuticals and was previously Chief Financial Officer of PharMetrics Inc., a leading patient-based pharmacy and medical claims data informatics company. He was also Chief Financial Officer at ProScript, where Velcade® (bortezomib), a therapy widely used for the treatment of the blood cancer multiple myeloma, was discovered. David serves on the Board of Directors of Dyne Therapeutics, Gemini Therapeutics, Point BioPharma, and Vor Biopharma. A Certified Public Accountant, David received his BS in business administration from Northeastern University and an MS in taxation from Bentley University.

Rusty is President and Chief Executive Officer of Walking Fish Therapeutics and Venture Partner at Quan Capital. Rusty founded Five Prime Therapeutics and has served as Five Prime’s Executive Chairman, President and Chief Executive Officer. Rusty also co-founded COR Therapeutics, a biotechnology company focused on cardiovascular disease. Previously, Rusty worked at Chiron Corporation, now Novartis Vaccines and Diagnostics. Rusty has served on the faculty of the University of California, San Francisco; Harvard Medical School; and Massachusetts General Hospital. He is a member of the National Academy of Sciences and a fellow of the American Academy of Arts and Sciences. Rusty is currently on the Board of Directors of Protagonist Therapeutics and Neoleukin Therapeutics and has served on the Board of Directors of Chiron, COR Therapeutics and Beckman Coulter. Rusty received a BS from Rice University and MD and PhD degrees from Duke University.

Derek is President and Chief Executive Officer at Solasta Ventures and a member of the Board of Directors of Solasta. Derek is as member of the Board of Directors of Trefoil Therapeutics, and has served on the Board of Directors of Clearside Biomedical. Prior to Solasta, Derek managed investments with RBS Citizens, Berwind Private Equity, and Kibo Capital. Derek received a Master of Finance from Boston College and a MBA from Babson College. Derek also received a BS in Chemical Engineering from Yonsei University in South Korea.

Investors

Our investors to date have helped drive innovation, fund clinical trials and supported our growth. Collaboration is crucial to our mission. If you would like to learn more about partnering with Arcellx, please contact the investor relations group at [email protected].

NEA
novo
SR One
takeda
ajuib
Quan
Clough Capital Partners
mirae
JVC
LG Technology Ventures

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